This is a systematic condition which occur as a result of the complicated life-threatening allergy. Onset is very fast from seconds to minutes after allergic substance exposure.


Sign and symptoms usually arises very soon after the exposure of triggering stimuli but it may be delayed for hours. Anaphylaxis presents as;

  • Inflammation on skin leading to the development of hives and patches of redness accompanied by itching
  • Sometimes skin turns paleAdult Still's Disease
  • Drop in blood pressure
  • Problematic breathing due to swollen airway
  • Low and weak pulse
  • Digestion problems leading to diarrhea, vomiting and nausea

Main cause of this reaction is overactive immune system of the body. Mainly this type of reaction rarely occur after some allergic reaction but when allergic reaction become severe it lead to the development of anaphylaxis throughout the body. When body recognize non dangerous substance as harmful and excessively stimulated this is when all the balance of immune system gets troubled. There are many stimuli for allergic reaction like foods, bee sting, latex gloves, milk, pet dander or even physical work out can lead to this complication. Anaphylaxis can become severe enough to inhibit breathing.


Diagnosis depends upon detailed history about allergy to any kind of food or substance, previously induced allergic reaction and complete general physical examination. Other tests include;

  • Blood test to check the value of some enzymes like trytase in the blood which are indicator of anaphylaxis.
  • Skin prick test is prescribed to determine particular allergen.

Treatment options include;Anaphylaxis

  • Injection of adrenaline to ease the allergic symptoms.
  • Oxygen supplies to aid in breathing.
  • Intravenous administration of antihistamines and corticosteroids to help slow down inflammatory process.
  • For problematic breathing Beta agonist are administered.
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