Carcinoma of Unknown Primary Origin


Carcinoma of Unknown Primary Origin

It is defined as the cancer of unknown origin and the location of cancer is difficult to diagnosis by doctors. Usually cancer differentiate as primary and secondary cancer. But in this type primary site is difficult to find by routine procedure.


Signs and symptoms of carcinoma of unknown primary include:Carcinoma of Unknown Primary Origin

  • Pain
  • Frequent urge of urination
  • Night sweats
  • Cough
  • Fever
  • Weight loss
  • Lump felt in the skin
  • Changing bowel habits


The exact causes of cancer are still unknown but mutation in the DNA of the cells of any organ and tissue is the only causes responsible of the cancer formation. Mutation make the cell to grow in un-controlled fashion rapidly. Cells produce as a result of mutation are abnormal in morphology and in function.


Diagnostic tests include:

  • Imaging test to check the extend of tumor.
  • Urine test to rule out the other causes.
  • Blood test to check the complete count of blood.
  • Endoscopy to visualize the inner condition of body.
  • Biopsy of suspected tissue


Treatment depend upon the overall health condition and severity of the symptoms. Treatment options include:

  • Surgery to remove the whole affected organ or cancerous tissue.
  • Drugs to blocked the hormones produce by the certain tumor types which produce the signs and symptoms.
  • Radiotherapy to killed the tumor cells with the help of radiations.
  • chemotherapy


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