Monoclonal Gammopathy of Undetermined Significance

Monoclonal Gammopathy of Undetermined Significance

In this condition there is increase in abnormal protein called monoclonal protein also known as M protein in your blood. This Protein formed in your bone marrow or soft tissues that produce blood protein.


There is no specific signs and symptoms of this condition exist sometimes people developed nerve problems or skin rash, numbness or tingling.


The exact cause of MGUS is still unknown but it may be assumed that certain environmental and genetical changes may play the role in the development of disease.


Complications are rare, following complications occurred in some people:


Diagnostic tests include:

  • Imaging tests
  • Bone marrow test to check the cell type and extend of disease
  • Urine test to detect the proteins
  • Blood tests

MGUS generally does not required any treatment but your doctor recommend you to monitor your health after every six months. Medications for osteoporosis will be helpful for pain in bones.

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