Prader-Willi Syndrome

It is inherited genetic disorder which affects the physical, behavioral, and mental health. The main symptoms of Prader Willi syndrome are a persistent sense of hunger which usually start after 2 years of age.

Symptoms

Signs and symptoms of Prader Willi syndrome include:

Poor sucking reflex
Different facial features
Hypotonia (poor muscle tone)
Poorly developed genitals
Fatigue
Poor response of baby
Food cravings after 2 years of age
Cognitive impairment
Speech problem
Poor physical development
Sleep problem

Causes

It is a genetic condition which is cause by mutation in certain genes. Prader Willi syndrome occurred due to the mutation in particular genes located on chromosome number 15. It is usually involved paternal chromosome 15.

Complication

If left untreated it may cause the following complications:

Diagnosis

After taking history your and conduction general physical examination your doctor will recommend the genetic testing to confirm the diagnosis by checking chromosomal mutations.

Treatment

There is good prognosis if this condition is diagnosed early and treatment will be started early. Treatment options include:

Sex hormone treatment for underdeveloped genitals.
Nutrition therapy for infants
Human growth hormone therapy to increase growth and increase muscle tone
Weight management treatment to prevent diabetes mellitus
Mental health care through psychiatrist
Treatment for sleep problems

Lifestyle and home remedies

Home remedies include:

Take proper medicine
Eat healthy food
Exercise daily
Take rest
Avoid unnecessary activities

Prader-Willi Syndrome