Progeria, Hutchinson-Gilford syndrome


It is also known as Hutchinson-Gilford syndrome, in which children starts aging in first two years of life which is abnormal behavior of development. Progeria is a rare inherited disorder which include genetic mutations. The cause of death is usually heart diseases and stroke.


Signs and symptoms of progeria include:Progeria Symptoms Causes Treatment

  • High-pitched voice
  • Visible veins
  • Hair loss
  • Small lower jaw
  • Narrowed face
  • Retarred growth
  • Prominent eyes
  • Small height and weight
  • Wrinkled skin
  • Insulin resistance
  • Hip dislocation
  • Hearing loss
  • Stiff joint
  • Cardiovascular disease

Progeria is a genetic disorder which is inherited in nature. There is mutation in gene name Lamin A which formed protein which is required to hold cell nucleus together. Defected lamin A gene called progerin which make cell’s nucleus unstable.


After taking history and doing general physical examination your doctor might recommend the following test to diagnose this syndrome:

  • Hearing test
  • Visual acuity test
  • Anthropometric measurement
  • Measure vital signs like pulse rate, blood pressure and respiratory rate
  • Blood test to see the complete blood count
  • Genetic testing to confirm the genetic mutation

There is no cure for genetic disease and syndrome. But following treatment options will help to reduce the signs and symptoms:

  • Occupational therapy helps in mobility
  • Aspirin to prevent the thrombus formation and reduce risk of stroke
  • Nutiriton assessment
  • Dental hygiene
  • Certain other medications like cholesterol lowering drugs, drugs for hypertension etc.
Lifestyle and home remedies

Following tips will help you:

  • Use sunblock to prevent skin damage
  • Avoid sedentary lifestyle
  • Stay hydrated
  • Vaccinate your child properly
  • Take care the nutrition of your child
Scroll to Top